Which of the following conditions is NOT associated with keratoconus in the T-DOME mnemonic?

The condition that is NOT associated with keratoconus in the T-DOME mnemonic is diabetes mellitus. Keratoconus is a progressive eye disorder affecting the cornea, and it has been linked with various syndromic conditions that involve connective tissue and structural abnormalities.

In the context of the T-DOME mnemonic, conditions like osteogenesis imperfecta, Turner syndrome, and Ehlers-Danlos syndrome are all associated with keratoconus due to their effects on connective tissue integrity or structural properties. For instance, Ehlers-Danlos syndrome is characterized by hyperelastic skin and joint hypermobility, which can influence corneal shape. Osteogenesis imperfecta involves collagen abnormalities that may similarly predispose individuals to corneal deformation. Turner syndrome is associated with various ocular alterations, including keratoconus.

On the other hand, diabetes mellitus primarily affects the vasculature and metabolic processes rather than connective tissue or structural integrity. While it can lead to various ocular complications, such as diabetic retinopathy or cataracts, it is not specifically recognized as a risk factor for keratoconus. Hence, diabetes mellitus does not belong in the context of the T-DOME mnemonic related to keratoconus.