Which factor is NOT part of the causes listed for angioid streaks?

Angioid streaks are known to be associated with a variety of systemic diseases that can affect the elastic tissue in the body, particularly the Bruch's membrane in the eye. The correct answer indicates that histoplasmosis is not recognized as a cause of angioid streaks. The primary conditions associated with the development of angioid streaks include Paget's disease, which is a disorder of bone remodeling; idiopathic sources, which refer to cases without a known cause; and sickle-cell disease, which can lead to various ocular complications due to changes in blood flow.

Histoplasmosis is primarily an infectious condition caused by the fungus Histoplasma capsulatum, affecting primarily the lungs and occasionally causing ocular complications such as chorioretinitis, but it does not directly lead to the formation of angioid streaks. The other conditions listed have a well-established connection to the deterioration of elastic fibers and the subsequent development of angioid streaks, which is not the case with histoplasmosis. Understanding the specific pathophysiological mechanisms that link these diseases to angioid streaks helps clarify why histories of these particular conditions provide a context for their association.