In which layer of the skin is the stratum granulosum found?

The stratum granulosum is indeed located in the middle layer of the epidermis. This layer is crucial in the process of keratinization, where keratinocytes begin to lose their viability and start to flatten and dehydrate, contributing to the skin's barrier function. Located above the stratum spinosum and below the stratum lucidum (in thick skin) or the stratum corneum (in thin skin), its position is essential for the overall structure of the epidermis.

The keratinocytes within the stratum granulosum contain granules that are instrumental in the formation of keratin and the lipids that help waterproof the skin. This layer acts as a transition area where the cells undergo significant changes before ultimately reaching the outermost layer of the skin.