Hydroxychloroquine can cause which type of keratopathy?

Hydroxychloroquine is known to cause whorl keratopathy, also known as corneal verticillata. This condition is characterized by the presence of distinctive, whorl-like patterns in the epithelial layer of the cornea, resulting from the accumulation of the drug within the corneal tissues.

The formation of whorl keratopathy typically occurs without significant symptoms, which is important for clinicians to recognize during routine eye examinations of patients on hydroxychloroquine. The specific pattern and the time frame in which it can occur are important indicators for healthcare providers to monitor potential ocular side effects of the medication.

Understanding this can help in the early identification and management of potential complications in patients taking hydroxychloroquine, which is often prescribed for conditions like rheumatoid arthritis and lupus. Monitoring vision and performing regular eye exams can aid in preventing long-term visual impairment related to this drug.